- "The game. They say a person either has what it takes to play, or they don't. My mother was one of the greats. Me on the other hand... I'm kinda screwed. Like I said I'm screwed. I can't think of any one reason why I want to be a surgeon. But I can think of a thousand reasons why I should quit. They make it hard on purpose. There are lives in our hands. There comes a moment when it's more than just a game. And you either take that step forward or turn around and walk away. I could quit, but here's the thing... I love playing the field."- Meredith Grey
Meredith Grey, Izzie Stevens, George O'Malley, Cristina Yang and Alex Karev become interns at Seattle Grace Hospital. Meredith discovers that her one night stand was actually with one of her bosses and she and her new friends discover that being a surgeon isn't as easy or fun as they though it would be.
A woman named Meredith wakes up from her couch. She wraps a towel around her and begins to pick up her clothes. She throws a cushion on a man, who wakes up sleepily and passes her bra to her. Meredith is embarassed but tells him to get dressed. They make small talk while he gets dressed. Apparently, she is going to be late on her first day of her new job. He compliments her on her house, but she says it isn't here. It was her mother's and she is selling it. He tells her he is sorry and she quickly explains her mother is not dead. She then says they don't have to do the thing where they pretend to care. She goes to see him off but forgets his name. He quickly re-introduces himself as Derek and she tells him that she is Meredith. She then runs upstairs to shower.
A short while later, Meredith leaves her car and catches up with the other group of new interns at Seattle Grace Hospital. The Chief concludes his tour by saying that the next seven years will be the best and worst of their lives.
In the locker room, Meredith bonds with another intern, Cristina Yang. They discover that they have the same attending, Bailey or "The Nazi". Overhearing the conversation, another introduces himself as George O'Malley. He talks nervously and tells Meredith that they met last night. He describes what she was wearing but quickly stops when he realises they think he is gay. The three interns (along with another intern, an ex-model, Isobel Stevens) are called out to go to Bailey. Walking up to Bailey, they are shocked to see she is a woman (and not a nazi either). Isobel suggests that the nickname may be professional jealousy. Cristina scoffs nevertheless, Isobel introduces herself to Bailey, telling her that she is Isobel Stevens but that everyone calls her Izzie. Bailey ignores the introduction, shows them their equipment, gives them a short tour and tells them her rules. She then receives a page and she and the interns run onto the roof. On the roof, a chopper lands and gives details on a patient (Katie Bryce) who is having seizures. In the hospital, the interns and nurses inject Katie who finally stops moving. Another doctor, Preston Burke, walks in and describes her as a wet fish on dry land. He then orders them to do all the basic tests. George is work ups, Christina to do labs, Meredith is assigned to Katie Bryce and to get her a CT. Izzie is ordered to perform rectal exams by a smiling Bailey.
Izzie performs the recal examinations, Cristina gets the test results (still managing to hint to Bailey she would like a surgery), George tries to perform a simple procedure on a patient. Getting tiresome, Burke pushes him out of the way and does it himself. George then jokingly says that Burke himself probably messed up a lot at first too. Through gritted teeth, Burke smiles and tells George hes going to have fun with him, George gulps. Meanwhile Meredith is lost in the hospital with Katie continuously talking about the beauty pageant shes missing and how she was great at it other than when she fell over doing rhythmic gymnastics and occasionally stopping to tell Meredith that she is lost. A group of interns are sitting in the canteen (after 7 hours of their first shift) when Izzie says that she is screwed because a resident already hates her but George sympathises by saying he already has attendings hating him. Cristina then interrupts to ask if anyone else knew that Merediths mother is the famous surgeon Ellis Grey, who performed wonderful surgeries, wrote books and even won the Harper Avery Award. The conversation is quickly cut short by Meredith who tells everyone that Katie is unbearable. Preston Burke then arrives at the table to say he gets to choose one intern to assist him in a surgery. He picks George to scrub in on an apendectomy and then walks away.
Miranda Bailey complains to Burke about his decision saying that O'Malley barely made it into the program. He insists that if he terrorises one that the rest will fall in place but Bailey continues to attempt to persuade him. Katie Bryce's parents walk into her room. After making sure Katie feels okay their question Meredith about if she may need surgery. Meredith quickly explains that she isn't the doctor. She goes to Bailey to find Burke but he is off the case so she directs Meredith to the new attending on the case, Dr. Shepherd. Meredith looks over at him just as he looks up and Meredith quickly walks away as Dr. Shepherd is her one-night stand, Derek.
Derek catches up with her and pulls her into a stairwell. Meredith quickly decides to pretend it never happened, Derek instead says that she just took advantage of him. She starts to disagree but he quickly asks her if she wants to take advantage of him the next Friday. Meredith smiles but says no that it is inappropriate and walks away.
George is in the operating room and up in the gallery the other interns start making bets against him but Meredith quickly defends him. George starts the procedure and it runs perfectly until the very end where he accidentally pulls the purse strings too hard and breaks them. She starts to bleed but can't think what to do. After a few seconds, Burke pushes him away and finishes up the procedure. In the gallery the interns nickname George, 007 (license to kill). The interns look from thegallery.Added by 2Anthony4After the procedure, George worries about being nicknamed 007. He is being consoled when Meredith is paged and leaves as she got a 911 forKatie Bryce. George says he should have gone into geriatrics but Cristinasays geriatrics is for losers who never have sex and live with their mothers. George then quietly mutters to Izzie that he really needs to get a new place. Meredith runs through the hospital to see that Katie is fine and that she faked a seizure and wants Meredith to call someone. Annoyed,Meredith leaves.
Nurse Tyler asks a staring Izzie what she needs and she replies by saying that Mr. Jones has chunky veins and he needs antibiotics. She should start a central line but doesn't know how. Tyler smiles and tell her since the sleeping Miranda Bailey is the on call resident then Izzie has to wake her up. Timidly, Izzie walks over, Bailey asks if the patient is dying and when Izzie says no, she goes back to sllep. After a few seconds, she gets up grumpily and starts the central line. She then tells Izzie that the next time she is woken up the patient better be so close to death that he has a tag on his toe. Bailey sleeps.Added by 2Anthony4Another intern, Alex Karev, is staring at a patients chart he tell the nurse they have pneumonia and to start the antibiotics. The nurse asks if hes sure and he sarcastically asks if she went through 4 years of medical school. He walks over to Meredith and says he has Jeremy as his as his resident but Meredith just says that the patient may not have pneumonia, it may be splinting. Alex then calls her a nurse, Merdith gets insulted but has to answer her page, another 911 from Katie. Alex wonders to another intern if shes single and George says they're friends. Alex quickly cuts across and tells George to just stop talking.
Meredith runs into Katie's room where she is shocked to see Katie having severe multiple seizures. The drugs administrated didn't do anything so she tell a nurse to page Bailey and Shepherd. When the drugs still have no effect, she charges the paddles. On the fourth try, Katie's heartbeat and blood flow are normal. Shepherd then arrives and tells Merdith to leave. Bailey then walks by and lectures Meredith but Meredith ignores her and continues to walk briskly out the hospital doors. Worriedly, Cristina follows and is shocked to see Meredith throw uop against a tree. Meredith walks back into the hospital and tells Cristina not to tell anyone.
Back in the hospital (hour 24) , Shepherd explains to Katie's parents that it may not be a seizure disorder. Her parents tell Shepherd they want somebody else on the case because he isn't working hard enough. 24 hours into the interns' shift.Added by 2Anthony4In another area of the hospital, Burke explains to a patient the procedure. He will put him on bypass, fix his heart and then hes done. Gloria (Tony's wife) asks if she has to worry but Burke assures her that he is very good at what he does although it is surgery and does involve risks. He walks off but Gloria is still worried so George then consoles her and promises her that it will be okay and Tony will sail through the surgery.
While waiting impatiently for Dr. Shepherd, Cristina sutures a banana. She then calls George 007 when he laughs, but she quickly apologizes saying she gets mean when she's tired. Shepherd then walks in and explains that Katie is having seizures with no visible cause; she is a ticking clock. The intern who finds out the cause will get to scrub in on the advanced surgery. All the interns take copies of the chart.
Alex Karev walks up and asks the nurse if she paged him, she says yes and that the patient in 4B still isn't responding to antibiotics and they should have worked by now, he ignores it, saying she is old and asks the nurse not to page him again. Meredith walks away and Cristina runs up to her asking if she wants to work together so they can each get a 50% chance of getting in on the surgery. Mereedith accepts her proposal but says she doesn't want the surgery because she doesn't want to spend anymore time with Derek than possible.
In the hospital library, they try to figure out what is wrong, all the while Cristina asks why she won't spend time with Derek. Meredith eventually admits that they had sex. They move back to the discussion about Katie when Meredith realises something. She tells Cristina to get up and they go off to find Derek Shepherd. They confornt Derek telling him, although they have no proof, she may have an aneurism. As she fell but the fall was so minor her doctor didn't mention it. Derek goes to check it out and is shocked to discover that they were right, Katie was one in a million and is bleeding into her brain. He says Katie could have gone through her entire life without it being a problem and he conragulates the girls. He then picks Meredith to join him in the O.R. As soon as he leaces, Cristina glares at Meredith and storms away.
Meanwhile, Burke is operating on Tony Savitch and after a while, he leaves and goes out to George. George is shocked that Burke was so fast but Burke says the heart had too much dammage and Tony died. George is shocked and upset. He tell Burke he had promised Gloria that Tony would be okay. Burke is outraged saying that the only person who can keep a promise like that is God, he also tell George that he can be the one to tell Gloria. George tells Gloria that Tony has died.Added by 2Anthony4Izzie and Cristina are sitting down in private and Izzie tries to convince Cristina that maybe it wasn't Meredith's fault but Cristina stops her. Meredith appears and tries to apologize but Cristina says that Meredith can't come to her for absolution and at least she didn't get into med school bcause opf her mother or good surgeries because she slept with her boss. Meredith then storms off.
Derek is shaving Katie's head but Meredith says she doesn't want to scrub in but Derek insists that she does, that his decision wasn't because they had sex but because Meredith was Katie's doctor and on her first day at work she helped save her life.
Meredith and George are sitting on a window ledge outside wishing they had chosen different careers. George then says that his parents tell everyone that he is a surgeon as if its a big acomplishment. Meredith then says that when she told her mother that she wanted to go to medical school, she tried to talk her out of it because she didn't think Meredith had what it took so George shouldn't feel so bad.
The chief asks Alex a few questions and when Alex doesn't reply, he asks the room does anybody know the common causes of post-op fever. When nobody answers, Meredith does. The chief asks her what she thinks is wrong with the patient and Meredith correctly assumes, walking saying patient 4B is a prime candidate for a pulmonary embolis. The chief asks her how she would diagnose and she does so correctly, again. The Chief then tells Alex to do what Meredith said and then he is off the case. Walking away, the chief tells Meredith that he would know her anywhere and that she looks exactly like her mother. Meredith looks at Derek.Added by 2Anthony4Meredith walks to the O.R where Katie is being prepped. She observes admiringly and when Derek tells her to take a look, she does so and stares amazed. She then realizes it is more that a game and they make it hard on purpose. They have lives in their hands.
Outside the O.R when the surgery is finished, Cristina compliments her and after a few minutes, the girls make up. Almost as soon as Cristina walks away, Derek appears and Meredith tells him the surgery was amazing and such a high, much more than she expected. The two share a moment and Derek leaves saying that he will see her around.
Meredith later leaves the hospital with Cristina, Izzie and George and even later, she goes up the steps of a house through the rain. She tells a woman that she won't be selling her house anymore that she will get some roommates and that her fellow interns are really great. The woman asks Meredith is she her doctor but Meredith says no, but she is a doctor. The woman asks Meredith her name and Meredith reminds her. The woman then proceeds to tell Meredith that she thinks she was a doctor and Meredith smiles and tells her she was. The woman is Ellis Grey and she has Alzheimer's.
- Cristina Yang: Katie competes in beauty pageants.
- Derek Shepherd: I know that, but we have to save her life anyway.
- Miranda Bailey: Don't bother sucking up. I already hate you and thats not gonna change.
- "Portions for Foxes" - Rilo Kiley
- "Super Cool" - Bang Sugar Bang
- "They" - Jem
- "Dance" - The O.A.O.Ts
- "Ready to Rise" - Vaughan Penn
- "Life Is Short" - Butterfly Boucher
- "Into the Fire" - Thirteen Senses
This episode's title originated from the song A Hard Day's Night, originally sung by The Beatles.
- Out of all 20 surgical interns, only 6 were women.
- The interns have 48 hour shifts.
- Interns work every second day.
- Katie's room number was 3604.
- Tony Savitch had four children.
- Justin Chambers (Alex Karev) was not originally in the pilot.
- Ellen Pompeo ... Meredith Grey
- Sandra Oh ... Cristina Yang
- Katherine Heigl ... Izzie Stevens
- Justin Chambers ... Alex Karev
- T.R. Knight ... George O'Malley
- Chandra Wilson ... Miranda Bailey
- James Pickens Jr. ... Richard Webber
- Isaiah Washington ... Preston Burke
- Patrick Dempsey ... Derek Shepherd
- Billy Wood ... Senior Resident
- Joshua Bywater ... Intern #1
- Kathleen M. Darcy ... Anesthesiologist
- Noelle McCutchen ... Nurse #2
- Grinnell Morris ... Intern #4
- Sean Palmer ... Intern #3
- Brad Pennington ... Radiologist
- Sendhil Ramamurthy ... Intern #2
- Lynne Marie Stewart ... Pre-op Nurse
- Moe Irvin ... Nurse Tyler Christian
- Richard Gilbert-Hill ... Small Town Doc
- Randall Arney ... Mr. Bryce
- Laura Carson ... Gloria Savitch
- Gregory Erff ... Mr. Jones
- Joel Schmidt ... Gloria's Brother
- Skyler Shaye ... Katie Bryce
- Robbie Troy ... Mrs. Bryce
- David Vegh ... Tony Savitch
- Martin Ighani ... Rectal Exam Patient (uncredited)